Skip to search form Skip to main content You are currently offline. Some features of the site may not work correctly. Save to Library. Create Alert.

Author:Nekasa Voodoogami
Language:English (Spanish)
Published (Last):19 March 2019
PDF File Size:15.43 Mb
ePub File Size:20.80 Mb
Price:Free* [*Free Regsitration Required]

Phytochemical screening of stem bark and leaves of Gmelina arborea; and effect of aqueous and ethanolic extracts of Gmelina arborea stembark on hepatic and renal insufficiency in rats was assessed in this study. Phytochemical screening was carried out on the air-dried leaf, oven-dried leaf, air-dried stembark and oven-dried stembark samples. Sixty five 65 wister albino rats, Animals were starved, 24 hours prior to sacrifice and sacrificed on the 9th day after commencement of treatment.

Phytochemical screening results show the presence of alkaloid, flavonoid, tannin, saponin, cyanogenic glycoside, phytate, and carbohydrate. Saponin and carbohydrate were shown to be much higher in concentration than other phytochemicals. The percentage composition of cyanogenic glycoside and phytate were highest in air-dried stembark and oven-dried leaf samples, respectively.

All the Gmelina arborea extracts and extract mixture administered to both paracetamol and cisplatin treated animals, significantly, lowers both the activities of the SGOT and SGPT, and the levels of serum creatinine and urea. When administered alone, the aqueous and ethanolic extracts show little or no sign of toxicity. Thus Gmelina arborea extracts may have ameliorating effect on hepatic and renal insufficiency caused by paracetamol and cisplatin respectively, and any inherent toxicity may be reduced or eliminated through adequate heat treatment.

This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. Search: Search. Advanced Clipboard. Create file Cancel. Email citation To:. Format: Summary Summary text Abstract Abstract text.

Send email Cancel. Add to Collections Create a new collection Add to an existing collection. Name your collection: Name must be less than characters. Choose a collection: Unable to load your collection due to an error Please try again. Add Cancel. Add to My Bibliography My Bibliography.

Unable to load your delegates due to an error Please try again. Your saved search Name of saved search:. Search terms:. Test search terms. Would you like email updates of new search results? Email: change. Frequency: Monthly Weekly Daily. Which day? Send at most: 1 item 5 items 10 items 20 items 50 items items items. Send even when there aren't any new results. Optional text in email:. Save Cancel. Create a file for external citation management software Create file Cancel.

Cite Favorites. Abstract Phytochemical screening of stem bark and leaves of Gmelina arborea; and effect of aqueous and ethanolic extracts of Gmelina arborea stembark on hepatic and renal insufficiency in rats was assessed in this study.

Similar articles Toxicological studies on aqueous extract of Gmelina arborea in rodents. Kulkarni Y, Veeranjaneyulu A. Kulkarni Y, et al.

Pharm Biol. Epub Aug PMID: Phytochemical screening and acute toxicity evaluation of Telfairia occidentalis aqueous extracts on rats. Anthony OE, et al.

Pak J Pharm Sci. Gmelina arborea Roxb. Attanayake AP, et al. J Diabetes Res. Epub Jan 6. Amelioration of cisplatin-induced nephrotoxicity by extracts of Hemidesmus indicus and Acorus calamus.

Sandeep D, et al. Lazrishvili IL, et al. Klin Khir. PMID: Review. Show more similar articles See all similar articles. Cited by 1 article Marine macro-algae attenuates nephrotoxicity and hepatotoxicity induced by cisplatin and acetaminophen in rats. Sohail N, et al. Environ Sci Pollut Res Int. Epub Jun Animals Actions. Rats Actions. Rats, Wistar Actions. Substances Plant Extracts Actions.

Acetaminophen Actions. Cisplatin Actions. Copy Download.



We'd like to understand how you use our websites in order to improve them. Register your interest. Gmelina arborea Roxb. Chemical constituents from the bark have not been reported, although some chemical constituents from part of this plant heartwood, leaf, and root are known. In this study, the bark meal was successively extracted with acetone and methanol.


Gmelina arborea G. The present paper comprehensively reviewed the traditional uses, medicinal properties and chemical constituents isolated from G. The present article is aimed to provide information on recent advances and new foundations and direction for further exploring G. Pharmacological research reviewed that G. The main chemical constituents of G. The present review provides all the references and beneficial directions to explore further application of G. Wang Z.





Related Articles