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Phytochemical screening of stem bark and leaves of Gmelina arborea; and effect of aqueous and ethanolic extracts of Gmelina arborea stembark on hepatic and renal insufficiency in rats was assessed in this study. Phytochemical screening was carried out on the air-dried leaf, oven-dried leaf, air-dried stembark and oven-dried stembark samples. Sixty five 65 wister albino rats, Animals were starved, 24 hours prior to sacrifice and sacrificed on the 9th day after commencement of treatment.
Phytochemical screening results show the presence of alkaloid, flavonoid, tannin, saponin, cyanogenic glycoside, phytate, and carbohydrate. Saponin and carbohydrate were shown to be much higher in concentration than other phytochemicals. The percentage composition of cyanogenic glycoside and phytate were highest in air-dried stembark and oven-dried leaf samples, respectively.
All the Gmelina arborea extracts and extract mixture administered to both paracetamol and cisplatin treated animals, significantly, lowers both the activities of the SGOT and SGPT, and the levels of serum creatinine and urea. When administered alone, the aqueous and ethanolic extracts show little or no sign of toxicity. Thus Gmelina arborea extracts may have ameliorating effect on hepatic and renal insufficiency caused by paracetamol and cisplatin respectively, and any inherent toxicity may be reduced or eliminated through adequate heat treatment.
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Cite Favorites. Abstract Phytochemical screening of stem bark and leaves of Gmelina arborea; and effect of aqueous and ethanolic extracts of Gmelina arborea stembark on hepatic and renal insufficiency in rats was assessed in this study.
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PHYTOCHEMICAL AND PHARMACOLOGICAL PROFILE OF GMELINA ARBOREA: AN OVERVIEW
We'd like to understand how you use our websites in order to improve them. Register your interest. Gmelina arborea Roxb. Chemical constituents from the bark have not been reported, although some chemical constituents from part of this plant heartwood, leaf, and root are known. In this study, the bark meal was successively extracted with acetone and methanol.
Gmelina arborea G. The present paper comprehensively reviewed the traditional uses, medicinal properties and chemical constituents isolated from G. The present article is aimed to provide information on recent advances and new foundations and direction for further exploring G. Pharmacological research reviewed that G. The main chemical constituents of G. The present review provides all the references and beneficial directions to explore further application of G. Wang Z.