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Zotero Mendeley EndNote. Objective: Caloric restriction CR is a dietary regimen that restricts calorie intake while maintaining the essential nutritional requirements without disturbing the homeostasis of body. As well as prevention of obesity, CR has been shown to prevent age-related pathologies and delay the aging process. Materials and Methods: Wistar Albino, 40 male months rats were included and divided into 4 groups as: non-obese NK , non-obese caloric restricted ND , obese OK , obese calorie restricted OD groups.

At the end of 10th week the rats were anaesthetized, euthanized by taking blood from aorta. Obesity , calorie restriction , oxidative stres; antioxidant enzymes.

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J Lab Clin Med ; Caloric restriction, body fat and ageing in experimental models. Obes Rev. Obesity and hypertension have differing oxidant handling molecular pathways in age-related chronic kidney disease. Pediatrics ; Masoro EJ. Caloric restriction-induced life extension of rats and mice: a critique of proposed mechanisms. Biochim Biophys Acta. Ameliorative effects of dietary caloric restriction on oxidative stress and inflammation in the brain of streptozotocin-induced diabetic rats.

Clin Chim Acta. Factors affecting DNA damage caused by lipid hydroperoxides and aldehydes. Free Radic Biol Med. Sohal RS, Weindruch R. Oxidative stress, caloric restriction, and aging. Science ; 5; Barja G. Endogenous oxidative stress: relationship to aging, longevity and caloric restriction.

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Effect of dietary on the age-dependent changes in the expression of antioxidant enzymes in rat liver. Influence of age and caloric restriction on expression of hepatic genes for xenobiotic and oxygen metabolizing enzymes in the mouse.

Oxidative damage, mitochondrial oxidant generation and antioxidant defenses during aging and in response to food restriction in the mouse. Ageing Dev. Dietary restriction delays cataract and reduces ascorbate levels in Emory mice. Eye Res. DOI: Tam Metin.


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