Year , Volume 1 , Issue 3, Pages - Zotero Mendeley EndNote. Abstract en tr Atypical antipsychotics cause less frequently extrapyramidal system symptoms, neuroleptic malignant syndrome and hyperprolactinemia than typical antipsychotics. However hematological side effects such as leukopenia and neutropenia could occur during treatment with atypical antipsychotics.
|Published (Last):||24 April 2005|
|PDF File Size:||12.69 Mb|
|ePub File Size:||16.70 Mb|
|Price:||Free* [*Free Regsitration Required]|
Objective: Although atypical antipsychotics are well-tolerated and effective treatment options for schizophrenia, they have metabolic side effects, including weight gain and increased risk of Type II Diabetes Mellitus DM.
Adiponectin, produced exclusively in adipocytes, is the most abundant serum adipokine. Low levels of adiponectin are correlated with DM, insulin resistance and coronary heart disease. Usage of atypical antipsychotics may create a risk of metabolic syndrome. The aim of this study was to evaluate the effects of antipsychotic usage on parameters related to development of metabolic syndrome. All patients had been treated with atypical antipsychotics for at least 3 months and were in remission.
Results: Serum adiponectin levels were significantly lower p Conclusion: Our findings supported the hypothesis that the length of administration of atypical antipsychotics has an effect on metabolic changes.
They also highlight the fact that when investigating metabolic changes generated by atypical antipsychotic effects, the length of time that the patient has been on the atypical antipsychotics should also be considered.
Keywords: Atypical antipsychotics; Metabolic syndrome; Serum adiponectin levels; Usage duration. Graph showing the correlation between the usage duration of atypical antipsychotics and adiponectin….
Clipboard, Search History, and several other advanced features are temporarily unavailable. Search: Search. Advanced Clipboard. Create file Cancel. Email citation To:. Format: Summary Summary text Abstract Abstract text. Send email Cancel. Add to Collections Create a new collection Add to an existing collection.
Name your collection: Name must be less than characters. Choose a collection: Unable to load your collection due to an error Please try again. Add Cancel. Add to My Bibliography My Bibliography.
Unable to load your delegates due to an error Please try again. Your saved search Name of saved search:. Search terms:. Test search terms. Would you like email updates of new search results?
Email: change. Frequency: Monthly Weekly Daily. Which day? Send at most: 1 item 5 items 10 items 20 items 50 items items items. Send even when there aren't any new results. Optional text in email:. Save Cancel. Create a file for external citation management software Create file Cancel. Full-text links Cite Favorites. Abstract in English , Turkish. Figures Figure 1. Figure 1. Graph showing the correlation between the usage duration of atypical antipsychotics and adiponectin levels.
See this image and copyright information in PMC. Similar articles Adjunctive effects of aripiprazole on metabolic profiles: comparison of patients treated with olanzapine to patients treated with other atypical antipsychotic drugs. Wang LJ, et al. Prog Neuropsychopharmacol Biol Psychiatry. Epub Oct PMID: Association of adiponectin and metabolic syndrome among patients taking atypical antipsychotics for schizophrenia: a cohort study.
Bai YM, et al. Schizophr Res. Epub May 5. The relationship between serum adiponectin levels, cardiometabolic indices and metabolic syndrome in schizophrenia. Tay YH, Lee J. Tay YH, et al. Asian J Psychiatr.
Epub Apr Impact of atypical antipsychotic therapy on leptin, ghrelin, and adiponectin. Jin H, et al. Epub Jan Antipsychotic metabolic effects: weight gain, diabetes mellitus, and lipid abnormalities. McIntyre RS, et al. Can J Psychiatry. PMID: Review. Show more similar articles See all similar articles.
Full-text links [x] Free PMC article. Copy Download.
Atypical Antipsychotics Induced Metabolic Syndrome/Atipik Antipsikotiklere Bagli Metabolik Sendrom